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KMID : 0391520130210030152
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Journal of the Korean Child Neurology Society
2013 Volume.21 No. 3 p.152 ~ p.161
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The Diagnostic Value of Serum Monocyte Percentage in Young Infants Suspected of Meningitis
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Lee Ji-Ho
Kim Won-Seop
Kim Yong-Dae
Lee Ji-Hyuk
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Abstract
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Purpose: To avoid a unnecessary lumbar puncture, we tried to find a useful tool for prediction of meningitis in infants.
Methods: One hundred and twenty four patients underwent a lumbar puncture at Chungbuk National University Hospital from Jan 1, 2011 to Dec 31, 2011. We divided them into 2 groups by the evidence of meningitis, and compared laboratory findings and clinical manifestations.
Results:There were 30 patients for meningitis group and 94 patients for control group. Meningitis group revealed lower serum monocyte percentage (meningitis group 10.1+/-4.7%, control group 12.2+/-5.0%, P=0.049) than control group. Other laboratory findings and clinical manifestations showed no statistically significant differences between two groups.
Conclusion: Serum monocyte percentage could help to predict meningitis in young infants, but it is not enough to replace a lumbar puncture. We therefore think that it requires a more accurate non-invasive diagnostic tool to detect meningitis.
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KEYWORD
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Meningitis, Infant, Monocyte
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